abstract：:The study of focal central nervous system ischemia has been impeded by the lack of animal models that are both reproducible and simulate human ischemic strokes. To circumvent these problems, we have developed a rabbit spinal cord infarction model. Infarction of the caudal lumbar cord is produced by temporary occlusion...

journal_title：Stroke

authors： Zivin JA,DeGirolami U

更新日期：1980-03-01 00:00:00

abstract：:The external diameters of rat and rabbit basilar arteries were determined before and after formaldehyde fixation in relaxed and drug constricted vessels. Fixation usually resulted in an immediate vessel constriction followed by partial relaxation after several hours. However, the results were inconstant from vessel to...

journal_title：Stroke

authors： Hart MN,O'Donnell SL

更新日期：1980-01-01 00:00:00

abstract：:Nineteen unanesthetized sheep were given Evans blue dye or radionuclide and then were incrementally bled into hemorrhagic shock (BP less than 50/25) by withdrawal of blood over a period of approximately one hour. Four sheep served as controls for histologic data. Static nuclide brain scans performed in 6 bled sheep d...

journal_title：Stroke

authors： Bronshvag MM

更新日期：1980-01-01 00:00:00

abstract：:This investigation tests the hypothesis that the normal cerebral image obtained non-invasively during continuous inhalation of C15O2 is related to cerebral blood flow. Trace amounts of CO2 labeled with the positron-emitting radionuclide 15O were administered to 4 normal subjects at normo- and hypocapnia and to 2 of th...

journal_title：Stroke

authors： Ackerman RH,Subramanyam R,Correia JA,Alpert NM,Taveras JM

更新日期：1980-01-01 00:00:00

abstract：:A new technique is described for the autoradiographic determination of regional brain glucose metabolism employing 14C labeled glucose as substrate and measurement principles previously described for whole brain. Regional glucose values correlate closely with those reported for the 14C-deoxyglucose technique. The meth...

journal_title：Stroke

authors： Hawkins R,Hass WK,Ransohoff J

更新日期：1979-11-01 00:00:00

abstract：:Intravenously injected metaraminol induced a larger blood pressure increase in spontaneously hypertensive rats (SHR) than in normotensive controls (NR) when the pressure was raised from the same starting level. Cerebral blood flow (CBF) response in NR was either perfect autoregulation, partial autoregulation or "break...

journal_title：Stroke

authors： Johansson BB,Nilsson B

更新日期：1979-09-01 00:00:00

abstract：:Cerebral blood flow was studied in rabbits immediately following complete circulatory stasis of varying duration. Systemic arterial pressure was measured continuously. The postischemic circulation was examined both by an infusion of carbon black and, in separate experiments, by injection of 14C-antipyrine into the blo...

journal_title：Stroke

authors： Fischer EG,Ames A 3rd,Lorenzo AV

更新日期：1979-07-01 00:00:00

abstract：:The levels of lipid peroxides, determined as thiobarbituric acid reactive substances (TBARS), and the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), were examined in the blood from stroke-prone spontaneously hypertensive rats (SHRSP), with and without cerebral lesions, and normotensive W...

journal_title：Stroke

authors： Tomita I,Sano M,Serizawa S,Ohta K,Katou M

更新日期：1979-05-01 00:00:00

abstract：:The author reviewed electrocardiographic records of 150 patients with acute stroke and 150 age- and sex-matched controls, to assess the relative frequencies of ECG abnormalities among the pathophysiologic categories of stroke, and to distinguish new abnormalities at the time of the stroke from those noted on prior tra...

journal_title：Stroke

authors： Goldstein DS

更新日期：1979-05-01 00:00:00

abstract：:Serum dopamine-beta-hydroxylase (DBH) activity was measured in 34 patients with acute cerebrovascular disease. The serum level of DBH activity showed its highest value soon after the onset of stroke and then gradually decreased over the next few days. After reaching its lowest level, the DBH activity again showed a sl...

journal_title：Stroke

authors： Kanda T,Gotoh F,Yamamoto M,Sakai F,Takeoka T,Takagi Y

更新日期：1979-03-01 00:00:00

abstract：:In experiments carried out on adult rabbit "chest-head" preparations the volume changes of the exposed brain (BrV) were determined in repeated tests during a controlled increase of the systemic venous pressure (SVP) of about 13 mm Hg. The changes of both SVP and BrV were usually parallel at the onset of the experiment...

journal_title：Stroke

authors： Mchedlishvili G,Nikolaishvili L,Itkis M

更新日期：1979-01-01 00:00:00

abstract：:We have investigated the effects of a reduced regional or a reduced body temperature, on pial arteriolar response to a variety of vasoactive stimuli. This has been done by studying the effects of these stimuli on groups of mice with different body temperatures, or with different temperatures of the artificial cerebros...

journal_title：Stroke

authors： Rosenblum WI,Segreti AC

更新日期：1978-11-01 00:00:00

abstract：:Diphenyl-para-phenylenediamine (DPPD) is an antioxidant that has been shown to decrease liver damage due to the peroxidative process of carbon tetrachloride in rats and to ameliorate cold-induced cerebral edema in cats. Because lipid peroxidation disrupts the integrity of the plasma membrane, a process believed to occ...

journal_title：Stroke

authors： Butterfield JD,McGraw CP

更新日期：1978-09-01 00:00:00

abstract：:Cardiac arrhythmias were more frequent (p less than 0.001) in 312 stroke patients admitted to an intensive care stroke unit, than in 92 patients admitted to the unit and subsequently found not to have strokes. This significant difference remained when a stroke subgroup and the non-stroke group were matched for age, se...

journal_title：Stroke

authors： Norris JW,Froggatt GM,Hachinski VC

更新日期：1978-07-01 00:00:00

abstract：:Experimental regional cerebral ischemia was produced in the middle cerebral artery (MCA) territory in primates (M. mulatta) by macrosphere embolization. Determinations of percentage tissue dry weight and tissue sodium and potassium concentrations were obtained in samples from the ischemic and non-ischemic hemispheres ...

journal_title：Stroke

authors： Bremer AM,Yamada K,West CR

更新日期：1978-07-01 00:00:00

abstract：:The intact omentum of 13 monkeys was lengthened, placed subcutaneously, and laid on the left cerebral hemisphere prior to occluding the left middle cerebral artery. Two of these 13 monkeys developed left cerebral infarct and a right hemiparesis. Nine other monkeys had their left middle cerebral artery occluded without...

journal_title：Stroke

authors： Goldsmith HS,Duckett S,Chen WF

更新日期：1978-05-01 00:00:00

abstract：:Continuous-wave Doppler sonography is a reliable method for detecting severe subclavian stenosis and occlusion as well as subclavian steal. Intermediate stages leading to subclavian steal can also be detected. These are characterized by a cardiac-phase-dependent alternating flow direction in the vertebral artery. Some...

journal_title：Stroke

authors： von Reutern GM,Pourcelot L

更新日期：1978-05-01 00:00:00

abstract：:Cerebral cortical blood flow was measured in rabbits with the hydrogen clearance technique. The reactivity to CO2, tested by changing the end tidal CO2 (ETCO2) in steps from 2 to 6 volumes %, was highly dependent on the kind of anesthesia, being greatest under halothane and least under nitrous oxide. Reactivity to CO2...

journal_title：Stroke

authors： Scremin OU,Rubinstein EH,Sonnenschein RR

更新日期：1978-03-01 00:00:00

abstract：:Unilateral stimulation of the cervical sympathetic in dogs had no effect on cerebral blood flow (CBF) measured by the venous outflow technique. Since this technique measured CBF from both cerebral hemispheres, small changes induced by unilateral stimulation could have been masked by a large constant CBF measured from ...

journal_title：Stroke

authors： Barber BJ,Martin JS,Rapela CE

更新日期：1978-01-01 00:00:00

abstract：:A retrospective analysis of 248 patients with stroke (average age 67, range 17-98) admitted to a stroke rehabilitation unit over a sixteen month period showed that 80% of these patients were able to return home after an average length of stay (LOS) of 43 days. At discharge 85% of the group were ambulatory and 56% requ...

journal_title：Stroke

authors： Feigenson JS,McDowell FH,Meese P,McCarthy ML,Greenberg SD

更新日期：1977-11-01 00:00:00

abstract：:Five patients studied by the authors and 28 mentioned in the literature indicate that recurrent stenosis occurs in no less than 0.6% of patients after carotid endarterectomy. The pathology of the recurrent stenosis was stated in only 10 cases indicating atherosclerotic disease in various stages of development in 7 and...

journal_title：Stroke

authors： French BN,Rewcastle NB

更新日期：1977-09-01 00:00:00

abstract：:In 100 consecutive patients with acute cerebrovascular accident, due to cerebral thrombosis in 72, cerebral hemorrhage in 12, embolus in 6, and subarachnoid hemorrhage in 10, there were 90 who had electrocardiographic abnormalities during the first three days after admission, compared to 50% in a control group. The pa...

journal_title：Stroke

authors： Dimant J,Grob D

更新日期：1977-07-01 00:00:00

abstract：:The effect of ischemia on catecholamine and 5-hydroxytryptamine (5-HT) levels in brain cortex was examined in the gerbil stroke model. Unilateral common carotid artery occlusion produced bilateral decrease in cortical dopamine levels in gerbils both symptomatic and asymptomatic of cerbral ischemia. The 5-HT progressiv...

journal_title：Stroke

authors： Welch KM,Chabi E,Buckingham J,Bergin B,Achar VS,Meyer JS

更新日期：1977-05-01 00:00:00

abstract：:The effect of respiration on the cerebrovascular response to elevated intracranial pressure (ICP) was studied in anesthetized dogs. Total and regional cerebral blood flows were measured using labelled microspheres. In spontaneously breathing dogs total and regional cerebral blood flows increased when cerebral perfusio...

journal_title：Stroke

authors： Malik AB,Krasney JA,Royce GJ

更新日期：1977-03-01 00:00:00

abstract：:In normothermic anesthetized cats cerebral blood flow was interrupted completely for one hour by arterial clamping and induced hypotension. The effect of ischemia on the ionic gradients of the cerebral cortex was assayed by determining total cortical electrolytes and by recording the activities of extracellular potass...

journal_title：Stroke

authors： Hossmann KA,Sakaki S,Zimmerman V

更新日期：1977-01-01 00:00:00

abstract：:Platinum microelectrodes were used to measure H2 clearance in mouse brain, and the clearance curves were used to calculate regional cerebral blood flow (rCBF). The curves were usually biexponential, whether or not electrode placement was confined to the cortex. When calculated by the height over area method, rCBF in a...

journal_title：Stroke

authors： Rosenblum WI

更新日期：1977-01-01 00:00:00

abstract：:A 51-yearold man with moderate intermittent hypertension had a rapidly progressive, profound dementia in the absence of significant localizing neurological signs. Postmortem examination disclosed the vascular alterations and diffuse white matter degeneration which characterize subcortical arteriosclerotic encephalopat...

journal_title：Stroke

authors： Burger PC,Burch JG,Kunze U

更新日期：1976-11-01 00:00:00

abstract：:The effect of prostaglandin E1 on regional cerebral blood flow (rCBF) was studied with the intra-arterial 133Xe method in ten awake patients under local anesthesia. Measurements were taken from 16 areas of a hemisphere in seven patients, from 35 areas of a hemisphere in two patients and from 256 areas of a hemisphere ...

journal_title：Stroke

authors： Olesen J

更新日期：1976-11-01 00:00:00

abstract：:A new micro T-tube, 0.6 mm in outer diameter, has been constructed. Use of this tube has allowed 1-mm common carotid artery (CCA) bypass ofr periods of time up to 22 minutes. After bypass, scanning electron microscopic observation of sutured CCA endothelium showed widespread destruction, scattered attached platelets a...

journal_title：Stroke

authors： Gregorius FK,Rand RW

更新日期：1976-09-01 00:00:00

abstract：:Using a scintillation camera system, hemispheric and regional cerebral blood flow was measured repeatedly during the course after a stroke. In 20 patients who improved clinically mean hemispheric and regional flow and relative weight of rapidly perfused compartment increased, while these values decreased in 15 patient...

journal_title：Stroke

authors： Heiss WD,Zeiler K,Turnheim M,Podreka I

更新日期：1976-07-01 00:00:00

abstract：:Cerebrovascular ring-like fat deposition, which was noted only in hypertensive rats but never observed in normotensive rats even after they had been fed a high-fat cholesterol (HFC) diet for a long time, was successfully developed in the posterior communicating or other cerebrobasal arteries in normotensive rats fed a...

journal_title：Stroke

authors： Yamori Y,Horie R,Sato M,Fukase M

更新日期：1976-07-01 00:00:00

abstract：:Longitudinal stretch of the rabbit basilar artery produces local injury followed by prolonged circular constriction. After stretching and rapid release in vitro localized constrictions promptly occurred. This could be prevented by prior treatment with cyanide or calcium-free solution. Once produced, constrictions pers...

journal_title：Stroke

authors： Duckles SP,Bevan RD,Bevan JA

更新日期：1976-03-01 00:00:00

abstract：:Arteriolar diameters and venular erythrocyte velocities in the small pial vessels on the surface of the cat brain were measured by TV methods during induced epileptic seizures through a cranial window. Grand mal seizures maximally dilated arterioles and increased venular erythrocyte velocity up to 400%. High positive ...

journal_title：Stroke

authors： Myers RR,Intaglietta M

更新日期：1976-01-01 00:00:00

abstract：:A patient with diffuse and focal cerebral dysfunction was found to have absent peripheral pulses. Cerbral angiography revealed evidence of an arteritis with bilateral high grade carotid stenosis. When there was no laboratory confirmation of the arteritis, an iatrogenic etiology (ergotism) was suspected. This was later...

journal_title：Stroke

authors： Senter HJ,Lieverman AN,Pinto R

更新日期：1976-01-01 00:00:00

abstract：:An ocular pneumoplethysmograph was devised to measure the systolic pressure in the ophthalmic artery and to obtain calibrated pulse volume changes from the ocular globe, with simultaneous recording from both eyes. The instrument is self-contained and portable. It can be applied by paramedical personnel, and the graphi...

journal_title：Stroke

authors： Gee W,Oller DW,Wylie EJ

更新日期：1976-01-01 00:00:00

abstract：:The hydrogen clearance method was used to measure local and total cerebral blood flow (CBF) in the rhesus monkey before and for five hours after a simulated subarachnoid hemorrhage (SAH). CBF remained stable after SAH unless SAH was associated with a fall in cerebral perfusion pressure. In addition, cerebrovascular re...

journal_title：Stroke

authors： Martins AN,Doyle TF,Newby N,Kobrine AI,Ramirez A

更新日期：1975-11-01 00:00:00

abstract：:Cerebral blood flow (CBF) was determined in the rat under 70% nitrous oxide anesthesia and pentobarbital anesthesia. The application of the Fick principle technique of Kety et al. was modified utilizing 133Xe infused intravenously steadily for 30 seconds, at which time the animal was decapitated and the head frozen in...

journal_title：Stroke

authors： Matsumoto A,Namon R,Utsunomiya Y,Kogure K,Scheinberg P,Reinmuth OM

更新日期：1975-11-01 00:00:00

abstract：:Feline pial arteries larger than 100 mu in diameter constricted in response to cervical sympathetic nerve stimulation suggests or in response to topical application of norepinephrine. Smaller pial arteries were unresponsive to norepinephrine. This unresponsiveness persisted when norepinephrine was dissolved in CSF wit...

journal_title：Stroke

authors： Wei EP,Raper AJ,Kontos HA,Patterson JL Jr

更新日期：1975-11-01 00:00:00

abstract：:Two patients with left middle cerebral artery (MCA) distribution infarctions fulfilled the "hot stroke" criteria on sequential 99m Tc pertechnetate flow and static gamma camera studies. The radioisotopic finding of a paradoxical relative increased flow to the affected hemisphere correlated with serial angiography show...

journal_title：Stroke

authors： Yarnell PR,Earnest MP,Sanders B,Burdick D

更新日期：1975-09-01 00:00:00

abstract：:Regional cerebral ischemia was produced by common carotid artery occlusion in gerbils and by middle cerebral artery occlusion in dogs, cats, and squirrel monkeys. Anesthesia was induced with either pentobarbital or halothane and maintained for two to three hours after vessel occlusion. In acute studies, the effect of ...

journal_title：Stroke

authors： Michenfelder JD,Milde JH

更新日期：1975-07-01 00:00:00